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Keep away from concomitant usage of tucatinib with CYP3A substrates, in which small focus changes could cause serious or lifestyle-threatening toxicities. If unavoidable, minimize CYP3A substrate dose As outlined by solution labeling.Akutt og alvorlig allergisk reaksjon med symptomer som feber, utslett, opphovning, pustebesvær og blodtrykksfall. A